CHEMBL4863036


SMILES COc1ccc(-c2n[nH]cc2N2CCCNCC2)cc1
InChIKey CVHZKPJZRQJCSF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 272.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.52 5.52 5.52 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.73 5.73 5.73 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.8 5.8 5.8 ChEMBL