CHEMBL1182143


SMILES COc1ccc(-c2ccccc2)cc1OCCNC[C@H]1COc2ccccc2O1
InChIKey KHXNVNNRQVTRJN-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 7.21 7.21 7.21 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 6.87 6.87 6.87 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.96 7.96 7.96 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.82 7.82 7.82 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.25 8.25 8.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database