CHEMBL1182155


SMILES COc1cccc(OC)c1OCCNC[C@H]1COc2ccccc2O1
InChIKey GYSZUJHYXCZAKI-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 345.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Rat Adrenoceptors A pKd 6.92 6.92 6.92 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKd 9.2 9.2 9.2 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 9.17 9.17 9.17 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.24 8.24 8.24 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 9.49 9.73 9.98 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.29 9.29 9.29 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.39 9.39 9.39 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.61 8.61 8.61 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.61 8.61 8.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database