CHEMBL492871


SMILES O=C(CCCCCN1CCN(c2ccccc2-c2ccccc2)CC1)NCc1ccccc1
InChIKey LQFAQQWXFSOOQJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 441.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.78 7.78 7.78 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.79 6.79 6.79 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.3 6.3 6.3 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.3 6.3 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database