CHEMBL493465


SMILES C[C@H]1CN(Cc2cccc(-c3cc(CNC(=O)c4cccc(C#N)c4)ccc3F)c2)CCN1
InChIKey ZBEWUYNNNHETOS-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 442.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKd 9.6 9.6 9.6 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 6.5 6.5 6.5 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKd 8.1 8.1 8.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database