GSK1331268
| SMILES | Clc1cnc(nc1)N1CCN(CC1)Cc1nc2c(n1C)cccc2 |
| InChIKey | IXXZGBOSQDVMTC-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 3 |
| Molecular weight (Da) | 342.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| D4 | DRD4 | Human | Dopamine | A | pKi | 5.6 | 5.6 | 5.6 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pEC50 | 5.9 | 6.4 | 6.9 | ChEMBL |
| mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pEC50 | 6.9 | 6.9 | 6.9 | Guide to Pharmacology |