CHEMBL5028391


SMILES N=C(N)NCCC[C@@H](N)C(=O)NCCN1CCN(CCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey YFWMVRIRFFWDJL-MUUNZHRXSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 14
Molecular weight (Da) 660.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.17 6.17 6.17 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.4 8.4 8.4 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.6 6.6 6.6 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.23 9.23 9.23 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.93 7.93 7.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database