CHEMBL5028837


SMILES N=C(N)NCCC[C@@H](N)C(=O)NCCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey GHHSRBSZNGGGPF-GDLZYMKVSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 6
Rotatable bonds 15
Molecular weight (Da) 674.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.74 8.74 8.74 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.64 9.64 9.64 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 9.16 9.16 9.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database