CHEMBL507876


SMILES CCC[C@H]1C(=O)N([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)C(C)(C)C
InChIKey SCWYPKQWJXXMFD-NGDRWEMDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 602.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 6.0 6.0 6.0 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.08 6.08 6.08 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.72 7.72 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 6.1 6.1 6.1 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.26 6.26 6.26 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 8.1 8.1 8.1 ChEMBL