CHEMBL511161


SMILES CCCCNCCN1CN(c2ccccc2)C2(CCN(C3CCCc4c(Cl)cccc43)CC2)C1=O
InChIKey ZMEBBPWUVGTYBO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 494.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.74 8.74 8.74 ChEMBL
δ OPRD Human Opioid A pKi 5.88 5.88 5.88 ChEMBL
κ OPRK Human Opioid A pKi 7.85 7.85 7.85 ChEMBL
μ OPRM Human Opioid A pKi 6.85 6.85 6.85 ChEMBL
κ OPRK Human Opioid A pKi 7.85 7.85 7.85 PDSP Ki database
μ OPRM Human Opioid A pKi 6.85 6.85 6.85 PDSP Ki database
NOP OPRX Human Opioid A pKi 8.74 8.74 8.74 PDSP Ki database
δ OPRD Human Opioid A pKi 5.88 5.88 5.88 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database