CHEMBL5178499


SMILES Nc1nc(NCCNc2ccccc2)nc(NCCc2c[nH]c3ccccc23)n1
InChIKey GBMAWOZHLUHECK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 5
Rotatable bonds 9
Molecular weight (Da) 388.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.33 5.33 5.33 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.42 4.42 4.42 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.96 4.96 4.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.06 5.06 5.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database