CHEMBL5175637


SMILES Fc1ccc2c(Cc3nnc(Cc4c[nH]c5cc(F)ccc45)n3CCCc3c[nH]cn3)c[nH]c2c1
InChIKey VGAIZXCXOWVPIB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST2 SSR2 Human Somatostatin A pKi 6.19 6.19 6.19 ChEMBL
SST3 SSR3 Human Somatostatin A pKi 5.76 5.76 5.76 ChEMBL
SST1 SSR1 Human Somatostatin A pKi 7.01 7.01 7.01 ChEMBL
SST4 SSR4 Human Somatostatin A pKi 9.15 9.15 9.15 ChEMBL
SST5 SSR5 Human Somatostatin A pKi 5.03 5.03 5.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST4 SSR4 Human Somatostatin A pEC50 9.15 9.15 9.15 ChEMBL