CHEMBL1185017


SMILES COc1ccc2c(c1OCCNC[C@H]1COc3ccccc3O1)CCCC2
InChIKey QQNWVORTUJAROO-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 8.39 8.39 8.39 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 8.35 8.35 8.35 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.72 7.72 7.72 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 7.04 7.04 7.04 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.84 7.84 7.84 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.55 8.55 8.55 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.07 8.07 8.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database