CHEMBL5194826


SMILES Nc1nc(NCCc2c[nH]c3ccccc23)nc(N2CCN(c3ccccc3)CC2)n1
InChIKey ZVDYCLIYIAFRGQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.49 5.49 5.49 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.89 4.89 4.89 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.97 4.97 4.97 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.08 5.08 5.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database