CHEMBL4847020


SMILES CSCC[C@@H]1NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(C)=O)CSSC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(=O)CNC(=O)[C@H](CC(=O)O)NC1=O
InChIKey TZGBAANRHMTUSN-OVPJFHAQSA-N

Chemical properties

Hydrogen bond acceptors 24
Hydrogen bond donors 21
Rotatable bonds 27
Molecular weight (Da) 1424.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FZD2 FZD2 Human Frizzled F pEC50 7.7 7.7 7.7 ChEMBL
FZD1 FZD1 Human Frizzled F pEC50 8.0 8.0 8.0 ChEMBL