CHEMBL485384


SMILES CCCN(CCCCn1cc(-c2ccc(-c3ccccc3)cc2)nn1)C1CC=C(C#C[Si](C)(C)C)CC1
InChIKey ULYGZZPDPDMBCC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 510.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.24 5.24 5.24 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.89 7.89 7.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.16 6.17 6.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.16 6.17 6.17 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 7.89 7.89 7.89 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 5.74 5.74 5.74 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 5.75 5.75 5.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database