CHEMBL4857597


SMILES O=C1CCc2cc(CCCCN3CCN(c4ccccn4)CC3)ccc2N1
InChIKey NWOBFMIIGQBMFP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 364.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.61 7.62 7.64 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.83 6.85 6.87 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.69 6.69 6.69 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.25 6.26 6.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.35 8.37 8.39 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.28 6.29 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database