CHEMBL521523


SMILES C[C@H]1CN(Cc2cccc(-c3cc(CNC(=O)c4cccc(CC5CCNCC5)c4)ccc3F)c2)CCN1
InChIKey ZOZCBLGQKDOWFZ-QHCPKHFHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKd 11.0 11.0 11.0 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.5 10.5 10.5 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.3 8.3 8.3 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKd 8.6 9.15 9.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database