CHEMBL521687


SMILES CSc1ccccc1N1CCN(CCCCCC(=O)NCc2ccc(OS(C)(=O)=O)cc2)CC1
InChIKey DINBMKNNYLFNIR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 505.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.99 7.99 7.99 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.99 7.99 7.99 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.52 7.52 7.52 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.52 7.52 7.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database