CHEMBL522257


SMILES Cc1ccc2c(N3CCN(CCc4ccc5c(c4)N(C)C(=O)CO5)CC3)cccc2n1
InChIKey JAELRPUWEUXJPW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 416.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.7 8.9 9.3 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.5 9.83 10.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.4 9.87 10.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database