CHEMBL4866058


SMILES Clc1ccc2c(c1)CC(CCN1CCN(c3ccccn3)CC1)C2
InChIKey HVROSOVHMGPEMN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 341.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.34 7.34 7.35 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.56 5.56 5.56 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.61 6.61 6.61 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.21 8.21 8.21 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.91 5.91 5.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database