CHEMBL4876297


SMILES O=C1c2cc(Cl)ccc2CC1CCN1CCN(c2ccccn2)CC1
InChIKey BODKZKXTTLFUIE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.99 8.0 8.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.77 5.78 5.78 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.29 8.29 8.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.35 5.35 5.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database