CHEMBL48807


SMILES COc1ccccc1N1CCN(CNC(=O)c2ccccc2)CC1
InChIKey UWUCDMAWZWXZPY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 325.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.51 7.61 7.66 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.61 5.61 5.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.61 5.67 5.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.51 7.51 7.51 ChEMBL