GproteinDb

CHEMBL5273955

Agent/drug
Bioactivity

CHEMBL5273955

SMILES	C#Cc1cc(Nc2ccccc2C(=O)O)cc(C(F)(F)F)c1
InChIKey	ADYZEYUMYXAEPW-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	305.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_2B	ADA2B	Human	Adrenoceptors	A	pKi	4.80	4.80	4.80	ChEMBL
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	4.77	4.77	4.77	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TAS2R14	T2R14	Human	Taste 2	T2	pEC50	6.82	6.82	6.82	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL5273955

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.