CHEMBL492445


SMILES c1ccc(-c2ccc3c(c2)OC(C2=NCCN2)CO3)cc1
InChIKey CENDKGWAICPCEX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 280.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.0 6.0 6.0 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.9 5.9 5.9 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database