CHEMBL557330


SMILES COc1ccccc1N1CCN(C(=O)NC(=N)NCc2cccc3ccccc23)CC1
InChIKey JRLJFLWPLMJTPJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 417.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database