CHEMBL49395


SMILES c1cnc2cc(NC3=NCCN3)ccc2n1
InChIKey PVKUNRLEOHFACD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 213.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.49 5.49 5.49 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 4.91 4.91 4.91 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.66 6.66 6.66 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.85 5.85 5.85 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 4.74 4.74 4.74 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.51 6.51 6.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database