CHEMBL49876


SMILES N#Cc1ccccc1N1CCN(CNC(=O)c2ccc(Cl)cc2)CC1
InChIKey XISJOANVKUVBAU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 354.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.26 8.31 8.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.22 6.22 6.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.03 6.12 6.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database