CHEMBL51023


SMILES COc1ccccc1N1CCN(CNC(=O)c2ccc(C)cc2)CC1
InChIKey YBUOJMCAVXYQBO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.11 8.23 8.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.76 6.76 6.76 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.54 6.65 6.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.47 8.47 8.47 ChEMBL