CHEMBL514591


SMILES O=C(CCCN1CC2CC1N(c1ccc(Cl)cc1)C2)c1ccc(F)cc1
InChIKey ZBMQPMVISGXIDJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 372.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.29 6.29 6.29 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.66 6.66 6.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.77 6.77 6.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.77 6.77 6.77 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.66 6.66 6.66 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 6.29 6.29 6.29 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database