CYCLAZOCINE


SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1
InChIKey YQYVFVRQLZMJKJ-JBBXEZCESA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 271.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 8.89 9.95 10.28 ChEMBL
μ OPRM Rat Opioid A pKi 8.92 9.33 9.74 ChEMBL
δ OPRD Human Opioid A pKi 8.7 9.06 9.24 ChEMBL
κ OPRK Human Opioid A pKi 9.7 10.0 10.15 ChEMBL
μ OPRM Human Opioid A pKi 9.8 9.8 9.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.8 8.88 8.92 ChEMBL
μ OPRM Human Opioid A pEC50 8.35 8.38 8.4 ChEMBL
μ OPRM Human Opioid A pIC50 7.89 7.89 7.89 ChEMBL