CHEMBL5187578


SMILES O=Cc1ccc(-c2ccccc2OCF)cc1
InChIKey VWXWDHIJTXVFHJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 230.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 8.26 8.26 8.26 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.26 8.26 8.26 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.26 8.26 8.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.26 8.26 8.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 4.9 4.9 4.9 ChEMBL