CHEMBL59713


SMILES COc1cc(Br)cc(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1OC
InChIKey RYXXRKZWJMNUEJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 543.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.68 8.69 8.7 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.23 7.23 7.23 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.68 8.68 8.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database