CHEMBL5273955


SMILES C#Cc1cc(Nc2ccccc2C(=O)O)cc(C(F)(F)F)c1
InChIKey ADYZEYUMYXAEPW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 305.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 4.8 4.8 4.8 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 4.77 4.77 4.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TAS2R14 T2R14 Human Taste 2 T2 pEC50 6.82 6.82 6.82 ChEMBL