imbutamine


SMILES NCCCCc1cnc[nH]1
InChIKey VJSUMPPMFYQOMP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 139.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Guinea pig Histamine A pKd 7.7 7.7 7.7 ChEMBL
H3 HRH3 Human Histamine A pKi 8.37 8.39 8.4 ChEMBL
H3 HRH3 Human Histamine A pKi 8.4 8.4 8.4 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 7.84 7.93 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 8.13 8.44 9.2 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.05 7.2 7.5 ChEMBL