Ligand Data
Ligand
| Name | CHEMBL1289112 |
| SMILES | O=C(COCc1ccncc1)N1CCN(c2ccc(Cl)cc2)CC1 |
| InChIKey | VQWLSJSLTOXKEB-UHFFFAOYSA-N |
| Type | small-molecule |
| External Links |
Structure
Properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 5 |
| Molecular weight | 345.1 |
Bioactivity
| Receptor | Affinity (nM) | Potency (nM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
| mGlu5 | GRM5 | Human | Metabotropic glutamate | C (Glutamate) | 1300 | 1300 | 1300 | |||