CHEMBL55790


SMILES CN(CCN1C(=O)CC2(CCCC2)CC1=O)CCN(C)c1cc(Cl)ccc1Cl
InChIKey IOLUHLGDTSFFNV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 7.79 7.79 7.79 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.04 6.04 6.04 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.1 6.1 6.1 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.36 6.36 6.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database