CHEMBL71635


SMILES COc1ccc(N2CCN(CC[C@@H]3OCCc4cc(C(N)=O)ccc43)CC2)cc1
InChIKey OCFFXDBBLHVFSW-QFIPXVFZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 395.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Western lowland gorilla 5-Hydroxytryptamine A pKi 5.52 5.52 5.52 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.42 8.42 8.42 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.61 6.61 6.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.49 6.49 6.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database