CHEMBL563078


SMILES Cc1cc2nc(C)c(CN3CCN(c4ccc(Cl)c(Cl)c4)CC3)n2c(C)n1
InChIKey OPCWNMLUZVXULW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 403.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.68 5.68 5.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.68 7.68 7.68 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.89 5.89 5.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.26 5.37 5.48 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.26 5.37 5.48 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.89 5.89 5.89 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database