CHEMBL78218


SMILES O=C(c1ccc(F)cc1)C1CCN(CCc2ccc(F)cc2)CC1
InChIKey IHYHXNKLWLTICM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 329.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.52 5.52 5.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.02 8.02 8.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database