CHEMBL564688


SMILES Cn1c(N2CCCC2)nc2c(CN3CCN(c4ccc(Cl)c(Cl)c4)CC3)c[nH]c2c1=O
InChIKey VXWWHYWZTKORBH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 460.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.47 8.47 8.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.32 6.32 6.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.24 6.33 6.42 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.24 6.33 6.42 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.32 6.32 6.32 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database