CHEMBL68720


SMILES O=C(NCCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2=O
InChIKey HTQLYZCPYPEYGO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 521.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.7 8.7 8.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.55 7.55 7.55 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.3 8.3 8.3 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.45 7.45 7.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database