CHEMBL568443


SMILES CCCN1Cc2cc(-c3nnn(-c4cccnc4F)c3C)ccc2C1=O
InChIKey NYDVTBHNZHBCKX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pKi 9.4 9.4 9.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 8.44 8.44 8.44 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.55 5.55 5.55 ChEMBL