CHEMBL56869


SMILES O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2ccccc2Br)CC1
InChIKey ZWLNTIYBKQAWAA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 433.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 8.8 8.8 8.8 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.91 6.91 6.91 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.42 6.42 6.42 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.89 8.89 8.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database