CHEMBL83617


SMILES NC(=O)c1ccc2c(c1)CCOC2CCN1CC=C(c2c[nH]c3cc(F)ccc23)CC1
InChIKey AYGLZYIWAZBQDC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 419.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.55 6.6 6.69 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.25 7.53 8.1 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.38 7.86 8.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.33 8.33 8.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database