CHEMBL71724


SMILES COc1ccc(N2CCN(CCC3OCCc4ccccc43)CC2)cc1
InChIKey IAUNACXRZSWWJT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 352.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Western lowland gorilla 5-Hydroxytryptamine A pKi 5.14 5.14 5.14 ChEMBL
D4 DRD4 Rat Dopamine A pKi 8.85 8.85 8.85 ChEMBL
D3 DRD3 Rat Dopamine A pKi 5.92 5.92 5.92 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.17 8.17 8.17 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.96 5.96 5.96 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.62 8.62 8.62 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.12 7.12 7.12 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.84 5.84 5.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database