CHEMBL57540


SMILES COc1ccccc1N1CCN(CCN2C=CC3(CCCC3)CC2=O)CC1
InChIKey NMZPGTCGQWMZBC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 8.5 8.5 8.5 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.88 6.88 6.88 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.53 7.53 7.53 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.63 7.63 7.63 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database