CHEMBL57546


SMILES O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2ccc(F)cc2)CC1
InChIKey YSLMGFFVMWWPSA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 373.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 7.62 7.62 7.62 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.59 6.59 6.59 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.85 7.85 7.85 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.21 6.21 6.21 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.82 7.04 7.27 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.66 5.66 5.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database