CHEMBL57868


SMILES N#Cc1ccc(Cl)cc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1
InChIKey GUJILKGAXBCELS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 9.7 9.7 9.7 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.77 7.77 7.77 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.39 6.39 6.39 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.53 7.53 7.53 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.3 6.3 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database