CHEMBL80246


SMILES C[C@H](N)CN1CCc2cc(F)c(C(F)(F)F)cc21
InChIKey HMGZRIYJGAGANE-ZETCQYMHSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 262.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 5.97 5.97 5.97 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.31 7.31 7.31 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.89 6.89 6.89 ChEMBL